名称：填充柱

固定相：多孔聚合物

规格：2m*1/8

型号：PQ/Porapak Q

粒度：60-80目

应用：HG/T 6052-2022混合制冷剂 R507 系列

HG/T 6052-2022混合制冷剂 R507 系列不凝气测定 谱图：




1,1,1,2-Tetrafluoroethane as a pharmaceutical excipient for polymer porous microsphere filled column

Details of 1,1,1,2-tetrafluoroethane as a pharmaceutical excipient for the application of polymer porous microsphere filled column:






Pharmaceutical excipient tetrafluoroethane (HFC-134a)





1、 Basic information



Product name: medicinal excipient 1,1,1,2-tetrafluoroethane



Molecular formula: CH2FCF3



Relative molecular weight: 102.03



Product standard: G/JHGF O1 J 20 209-2012



2、 Physical and chemical properties: it is a colorless gas with slight ether odor under normal temperature and pressure; Melting point - 103.15 ℃, boiling point - 26.1 ℃, liquid density 1.206g/cm3 (25 ℃); Generally, they are compressed into liquid and stored in steel cylinders, and their thermal properties are similar to R12. Ozone depletion potential (ODP) is 0, and global warming potential (GWP) is 1200.



3、 Product use:



1,1,1,2-tetrafluoroethane is the main substitute for CFCs sprays. At the same time, due to its low toxicity and non-flammability, it has been developed as a carrier for drug inhalers (i.e. medical aerosols). Anti-asthmatic aerosol used to treat asthma, COPD (chronic obstructive pulmonary disease) and respiratory tract infection; Nasal aerosol foam aerosol for treating allergic rhinitis; Oral and local aerosols (such as promoting neurosensitivity, enhancing tooth vitality and relieving pain), etc.




Haohan Chromatography (Shandong) Applied Technology Development Co., Ltd. used gas chromatography to determine non-condensable gas in 1,1,1,2-tetrafluoroethane (HFC-134a) in Chinese Pharmacopoeia 2020, with high column efficiency, good separation and satisfactory results.



Name: Filled Column

Stationary phase: divinylbenzene-ethylvinylbenzene polymer porous microspheres

Specification: 2m * 3mm

Particle size: 0.18-0.25mm

Application: determination of non-condensable gas in tetrafluoroethane in Chinese Pharmacopoeia 2020





Spectrogram of 1,1,1,2-tetrafluoroethane, a pharmaceutical excipient used in polymer porous microsphere filled column: