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产品名称: 安捷伦2m*Φ3 高分子多孔微球填充柱应用之药用辅料1,1,1,2-四氟乙烷
产品型号: 安捷伦2m*Φ3
品牌: 1356
产品数量:
产品单价: 面议
日期: 2023-01-28

安捷伦2m*Φ3 高分子多孔微球填充柱应用之药用辅料1,1,1,2-四氟乙烷的详细资料

高分子多孔微球填充柱应用之药用辅料1,1,1,2-四氟乙烷
高分子多孔微球填充柱应用之药用辅料1,1,1,2-四氟乙烷 详细信息:



药用辅料四氟乙烷(HFC-134a)

 

一、基本信息

产品名称:药用辅料1,1,1,2-四氟乙烷

分子式:CH2FCF3

相对分子量:102.03

产品标准:G/JHGF O1 J 20 209-2012

二、理化性质:在常温常压下是一种无色、有轻微醚类气味的气体;熔点-103.15℃,沸点-26.1℃,液体密度1.206g/cm3(25℃); 一般情况下均压缩成液态储存于钢瓶中,其热力性能与R12相似。臭氧减损潜能值(ODP)为0,全球变暖潜能值(GWP)为1200。

三、产品用途:

1,1,1,2-四氟乙烷是CFCs喷射剂的主要替代品,同时,由于它的低毒和不易燃性,被研制用于药物吸入剂的载体(即医用气雾剂)。用于治疗哮喘、COPD(慢性阻塞性肺病)和呼吸道感染的防治哮喘气雾剂; 用于治疗过敏性鼻炎的鼻用气雾剂 泡沫气雾剂;口腔与局部气雾剂(如:促进神经感受性,增强牙齿活力和舒缓疼痛)等。


浩瀚色谱(山东)应用技术开发有限公司,采用气相色谱法测定2020版中国药典1,1,1,2-四氟乙烷(HFC-134a)中不凝气,柱效高,分离好,结果满意。

名称:填充柱
固定相:二乙烯苯-乙基乙烯苯高分子多孔微球
规格:2m*3mm
粒度:0.18--0.25mm
应用:中国药典2020版四氟乙烷中不凝气测定



高分子多孔微球填充柱应用之药用辅料1,1,1,2-四氟乙烷 谱图:




1,1,1,2-Tetrafluoroethane as a pharmaceutical excipient for polymer porous microsphere filled column

Details of 1,1,1,2-tetrafluoroethane as a pharmaceutical excipient for the application of polymer porous microsphere filled column:






Pharmaceutical excipient tetrafluoroethane (HFC-134a)





1、 Basic information



Product name: medicinal excipient 1,1,1,2-tetrafluoroethane



Molecular formula: CH2FCF3



Relative molecular weight: 102.03



Product standard: G/JHGF O1 J 20 209-2012



2、 Physical and chemical properties: it is a colorless gas with slight ether odor under normal temperature and pressure; Melting point - 103.15 ℃, boiling point - 26.1 ℃, liquid density 1.206g/cm3 (25 ℃); Generally, they are compressed into liquid and stored in steel cylinders, and their thermal properties are similar to R12. Ozone depletion potential (ODP) is 0, and global warming potential (GWP) is 1200.



3、 Product use:



1,1,1,2-tetrafluoroethane is the main substitute for CFCs sprays. At the same time, due to its low toxicity and non-flammability, it has been developed as a carrier for drug inhalers (i.e. medical aerosols). Anti-asthmatic aerosol used to treat asthma, COPD (chronic obstructive pulmonary disease) and respiratory tract infection; Nasal aerosol foam aerosol for treating allergic rhinitis; Oral and local aerosols (such as promoting neurosensitivity, enhancing tooth vitality and relieving pain), etc.




Haohan Chromatography (Shandong) Applied Technology Development Co., Ltd. used gas chromatography to determine non-condensable gas in 1,1,1,2-tetrafluoroethane (HFC-134a) in Chinese Pharmacopoeia 2020, with high column efficiency, good separation and satisfactory results.



Name: Filled Column

Stationary phase: divinylbenzene-ethylvinylbenzene polymer porous microspheres

Specification: 2m * 3mm

Particle size: 0.18-0.25mm

Application: determination of non-condensable gas in tetrafluoroethane in Chinese Pharmacopoeia 2020





Spectrogram of 1,1,1,2-tetrafluoroethane, a pharmaceutical excipient used in polymer porous microsphere filled column: